New advance in breast cancer pathology and imaging

Future Oncol. 2019 Aug;15(23):2707-2722. doi: 10.2217/fon-2019-0017. Epub 2019 Jul 24.

Abstract

The improvement of knowledge concerning the pathology of breast cancer could provide the rationale for the development of new imaging diagnostic protocols. Indeed, as for the microcalcifications, new histopathological markers can be used as target for in vivo early detection of breast cancer lesions by using molecular imaging techniques such as positron emission tomography. Specifically, the mutual contribution of these medical specialties can 'nourish' the dream of a personalized medicine that takes into account the intrinsic variability of breast cancer. In this review, we report the main discoveries concerning breast cancer pathology highlighting the possible cooperation between the departments of anatomic pathology and imaging diagnostics.

Keywords: breast cancer; breast microcalcifications; molecular imaging; pathology; personalized medicine.

Publication types

  • Review

MeSH terms

  • Biomarkers, Tumor / analysis
  • Breast Neoplasms / diagnostic imaging*
  • Breast Neoplasms / pathology*
  • Early Detection of Cancer / methods*
  • Female
  • Humans
  • Molecular Imaging / methods*
  • Positron-Emission Tomography
  • Precision Medicine / methods

Substances

  • Biomarkers, Tumor