Screening for basal metabolic rate and visceral fat among postmenopausal osteoporosis with type 2 diabetes mellitus

Abstract

Background: In people with type 2 diabetes mellitus, there is an increase in basal metabolic rate (BMR) which is associated with level of glycaemic control. Women with postmenopausal osteoporosis have decreased BMR. The aim of the present study is to find the BMR using Meffin-St Jeor predictive equation in women with type 2 diabetes mellitus (T2DM) who have attained menopause with osteoporosis.

Materials & methods: 100 women who have attained menopause, who were diagnosed to have osteoporosis with type 2 diabetes mellitus were assessed for BMR using Meffin-St Jeor predictive equation. Detailed history of diabetes and menopause were obtained. Blood glucose value was measured using standard glucometers. Body composition for visceral fat (VF) was measured using bioelectrical impedance analysis. Level of physical activity of the participants was measured using global physical activity questionnaire (GPAQ).

Results: The median BMR of the participants was 1.075 (714, 1483.25). Statistically significant correlation was found between BMR and GPAQ (r_s = 0.731), BMR and VF (r_s = 0.678). However BMR was not correlated with FBS (r_s = 0.083) duration of diabetes (r_s = -0.046).

Conclusion: There is a decrease in BMR in women with T2DM with postmenopausal osteoporosis. BMR was significantly correlated with level of physical activity and visceral fat.

Keywords: Basal metabolic rate; Postmenopausal osteoporosis; Type 2 diabetes mellitus.