Stercufoetin A, new oleanane-type triterpenoid from the leaves of Sterculia foetida L

Nat Prod Res. 2021 Apr;35(7):1226-1231. doi: 10.1080/14786419.2019.1644508. Epub 2019 Jul 22.

Abstract

From the leaves of Sterculia foetida L., one new oleanane-type triterpenoid, named stercufoetin A (1) together with four known ones, vergatic acid (2), β-amyrin (3), oleanolic acid (4) and maslinic acid (5) were purified by diversely chromatographic methods. Their structures were proposed by HR-APCI-MS and NMR experiments. Compounds (2-5) were notified for the first time from this species. Compound 1 showed weak cytotoxic effect against three human cancer cell lines (MCF-7, HepG2 and HeLa) using SRB assay.

Keywords: Sterculia foetida; Sterculiaceae; stercufoetin A; triterpenoid.

MeSH terms

  • Carbon-13 Magnetic Resonance Spectroscopy
  • Cell Death / drug effects
  • Cell Line, Tumor
  • Humans
  • Oleanolic Acid / analogs & derivatives*
  • Oleanolic Acid / chemistry
  • Oleanolic Acid / isolation & purification
  • Oleanolic Acid / pharmacology
  • Plant Extracts / chemistry
  • Plant Leaves / chemistry*
  • Proton Magnetic Resonance Spectroscopy
  • Sterculia / chemistry*
  • Triterpenes / chemistry
  • Triterpenes / isolation & purification*
  • Triterpenes / pharmacology

Substances

  • Plant Extracts
  • Triterpenes
  • oleanane
  • Oleanolic Acid