Angiosarcoma of the thyroid: a light, electron microscopic and histoimmunological study

Hum Pathol. 1988 Jun;19(6):742-5. doi: 10.1016/s0046-8177(88)80183-7.

Abstract

A histologic, histoimmunological, and ultrastructural study of a primary angiosarcoma of the thyroid gland is reported. The occurrence of neoplastic cells positive for Factor VIII-related antigen and Ulex Europaeus Agglutinin-I and the presence in their cytoplasms of Weibel-Palade bodies are consistent with this diagnosis. These findings further support the view that primary angiosarcoma of the thyroid is a distinct pathological entity and should no longer be interpreted as a variant of a poorly differentiated carcinoma.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Antigens / analysis
  • Factor VIII / analysis
  • Factor VIII / immunology
  • Hemangiosarcoma / analysis
  • Hemangiosarcoma / pathology*
  • Hemangiosarcoma / ultrastructure
  • Humans
  • Immunohistochemistry
  • Lectins / analysis
  • Male
  • Plant Lectins*
  • Thyroid Neoplasms / analysis
  • Thyroid Neoplasms / pathology*
  • Thyroid Neoplasms / ultrastructure
  • von Willebrand Factor

Substances

  • Antigens
  • Lectins
  • Plant Lectins
  • Ulex europaeus lectins
  • von Willebrand Factor
  • Factor VIII