The advanced role of carbon quantum dots in nanomedical applications

Biosens Bioelectron. 2019 Sep 15:141:111158. doi: 10.1016/j.bios.2019.02.059. Epub 2019 Mar 7.

Abstract

Carbon quantum dots (CQDs) have emerged as a potential material in the diverse fields of biomedical applications due to their numerous advantageous properties including fluorescence, water solubility, biocompatibility, low toxicity, small size and ease of modification, inexpensive scale-up production, and versatile conjugation with other nanoparticles. Thus, CQDs became a preferable choice in various biomedical applications such as nanocarriers for drugs, therapeutic genes, photosensitizers, and antibacterial molecules. Further, their potentials have also been verified in multifunctional diagnostic platforms, cellular and bacterial bio-imaging, development of theranostics nanomedicine, etc. This review provides a concise insight into the progress and evolution in the field of CQD research with respect to methods/materials available in bio-imaging, theranostics, cancer/gene therapy, diagnostics, etc. Further, our discussion is extended to explore the role of CQDs in nanomedicine which is considered to be the future of biomedicine. This study will thus help biomedical researchers in tapping the potential of CQDs to overcome various existing technological challenges.

Keywords: Bactericidal; Bio imaging; Carbon quantum dots; Drug/gene delivery; Theranostics.

Publication types

  • Review

MeSH terms

  • Animals
  • Biosensing Techniques / methods*
  • Carbon / chemistry
  • Carbon / therapeutic use*
  • Drug Delivery Systems / methods
  • Humans
  • Nanomedicine / methods*
  • Nanotechnology / methods
  • Optical Imaging / methods
  • Quantum Dots / chemistry
  • Quantum Dots / therapeutic use*

Substances

  • Carbon