A Mini-review of the Genomes and Allergens of Mites and Ticks

Curr Protein Pept Sci. 2020;21(2):114-123. doi: 10.2174/1389203720666190719150432.

Abstract

Mites and ticks are associated with many human diseases including allergic diseases and scabies. With the recent advances in the high throughput DNA sequencing technology, many mitochondrial nuclear genomes of these species have been sequenced and the resulting genomic resources will certainly provide novel insights for the future investigation of the functionally important proteins and peptides in these species. In this mini-review, the current situation of mite and tick genomes is described and the future perspectives for the application of the genomic resources are discussed, especially including the novel identification and structural analysis of allergens.

Keywords: DNA sequencing; Mites and ticks; allergic disease; genome; identification of allergen; transcriptome..

Publication types

  • Review

MeSH terms

  • Allergens / genetics*
  • Allergens / immunology
  • Animals
  • Humans
  • Hypersensitivity / genetics
  • Hypersensitivity / immunology
  • Mites / genetics*
  • Mites / immunology
  • Ticks / genetics*
  • Ticks / immunology

Substances

  • Allergens