Discovery of a virus of the species Enterovirus F in goats

Arch Virol. 2019 Oct;164(10):2551-2558. doi: 10.1007/s00705-019-04331-9. Epub 2019 Jul 18.

Abstract

Here, we report two novel enteroviruses, designated as SD-S67 and SD-S68, isolated from a goat farm. Their complete genome sequences were determined and found to be 7455 and 7465 nucleotides in length, respectively. Molecular characterization revealed that SD-S67 is closely related to bovine enterovirus strain 261 and that SD-S68 to caprine enterovirus strain CEV-JL14. Phylogenetic analysis showed that SD-S67 clustered with members of the species Enterovirus F, and that SD-S68 clustered with enteroviruses of goats and sheep. Recombination analysis showed that SD-S67 is likely to have undergone several recombination events in the process of its evolution. To the best of our knowledge, this is the first report of an enterovirus F isolate from a goat and of a coinfection with enteroviruses of different species in the same goat herd.

MeSH terms

  • Animals
  • Cluster Analysis
  • Cytopathogenic Effect, Viral
  • Enterovirus / classification*
  • Enterovirus / genetics
  • Enterovirus / isolation & purification*
  • Enterovirus Infections / veterinary*
  • Enterovirus Infections / virology
  • Genome, Viral
  • Goat Diseases / virology*
  • Goats
  • Microscopy, Electron, Transmission
  • Phylogeny*
  • Recombination, Genetic
  • Sequence Analysis, DNA
  • Sequence Homology
  • Virion / ultrastructure
  • Virus Cultivation