[Systemic and local therapy options for sudden sensorineural hearing loss in diabetics]

HNO. 2019 Aug;67(8):639-648. doi: 10.1007/s00106-019-0704-9.
[Article in German]

Abstract

Sudden sensorineural hearing loss is not an emergency, but an urgency. Depending on severity, the disease may have a major impact on quality of life. Gold standard in Germany is a systemic, high-dosage glucocorticoid therapy. During oral or intravenous therapy with glucocorticoids, systemic side effects may occur. Especially in diabetics, this therapy may cause acute prominent disorders in glucose metabolism and therefore may be contraindicated. An alternative therapeutic option is intratympanic injection of steroids into the middle ear. Hereby the systemic side effects are absent and only local otologic complications may occasionally occur.

Keywords: Corticosteroids; Drug therapy; Hyperglycemia; Intratympanic injection; Prednisolone.

MeSH terms

  • Dexamethasone
  • Diabetes Complications
  • Germany
  • Glucocorticoids* / administration & dosage
  • Glucocorticoids* / adverse effects
  • Glucocorticoids* / therapeutic use
  • Hearing Loss, Sensorineural* / therapy
  • Hearing Loss, Sudden
  • Humans
  • Quality of Life
  • Salvage Therapy / methods*
  • Treatment Outcome
  • Tympanic Membrane

Substances

  • Glucocorticoids
  • Dexamethasone