Acute exercise does not improve immune response to HPV vaccination series in adolescents

Papillomavirus Res. 2019 Dec:8:100178. doi: 10.1016/j.pvr.2019.100178. Epub 2019 Jul 15.

¹ The University of Sydney, Faculty of Health Sciences & Charles Perkins Centre, Sydney, Australia. Electronic address: erika.goldbaum@sydney.edu.au.
² School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK.
³ The University of Sydney, National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases, Sydney, Australia; The University of Sydney, Discipline of Child & Adolescent Health, Faculty of Health and Medicine, Children's Hospital Westmead, Australia.
⁴ The University of Queensland Diamantina Institute, Faculty of Medicine, Brisbane, Australia.
⁵ The University of Sydney, Faculty of Health Sciences & Charles Perkins Centre, Sydney, Australia.

Abstract

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Acute exercise is known to enhance less immunogenic response immunogenic antigens.
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In a 3-dose HPV vaccine series, exercise did not change antibody titers.
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Potential effects of exercise during first dose in series yet to be examined.