KPC-31 expressed in a ceftazidime/avibactam-resistant Klebsiella pneumoniae is associated with relevant detection issues

J Antimicrob Chemother. 2019 Aug 1;74(8):2464-2466. doi: 10.1093/jac/dkz156.

Authors

Alberto Antonelli¹, Tommaso Giani^{1

2}, Vincenzo Di Pilato¹, Eleonora Riccobono¹, Gabriele Perriello³, Antonella Mencacci^{4

5}, Gian Maria Rossolini^{1

2}

Affiliations

¹ Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
² Clinical Microbiology and Virology Unit, Careggi University Hospital, Florence, Italy.
³ Endocrinology and Metabolism, Santa Maria della Misericordia Hospital, Perugia, Italy.
⁴ Medical Microbiology, Department of Medicine, University of Perugia, Perugia, Italy.
⁵ Microbiology Unit, Santa Maria della Misericordia Hospital, Perugia, Italy.

PMID: 31318973
DOI: 10.1093/jac/dkz156

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / pharmacology*
Azabicyclo Compounds / pharmacology*
Bacterial Proteins / analysis*
Bacterial Proteins / genetics
Carbapenem-Resistant Enterobacteriaceae / drug effects
Carbapenem-Resistant Enterobacteriaceae / enzymology
Carbapenem-Resistant Enterobacteriaceae / isolation & purification
Ceftazidime / pharmacology*
Drug Combinations
Humans
Italy
Klebsiella Infections / microbiology*
Klebsiella pneumoniae / drug effects
Klebsiella pneumoniae / enzymology
Klebsiella pneumoniae / isolation & purification*
Microbial Sensitivity Tests
beta-Lactam Resistance*
beta-Lactamase Inhibitors / pharmacology*
beta-Lactamases / analysis*
beta-Lactamases / genetics

Substances

Anti-Bacterial Agents
Azabicyclo Compounds
Bacterial Proteins
Drug Combinations
avibactam, ceftazidime drug combination
beta-Lactamase Inhibitors
Ceftazidime
beta-Lactamases
carbapenemase