Not All Lymph Nodes Are Created Equal

Carolyn A Thomson; Kathy D McCoy

doi:10.1016/j.immuni.2019.06.018

Not All Lymph Nodes Are Created Equal

Immunity. 2019 Jul 16;51(1):12-14. doi: 10.1016/j.immuni.2019.06.018.

Authors

Carolyn A Thomson¹, Kathy D McCoy²

Affiliations

¹ Department of Physiology and Pharmacology, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
² Department of Physiology and Pharmacology, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. Electronic address: kathy.mccoy@ucalgary.ca.

PMID: 31315030
DOI: 10.1016/j.immuni.2019.06.018

Abstract

Appropriate priming of tolerogenic or effector immune responses is crucial for intestinal homeostasis. Recently in Nature, Esterházy et al. (2019) reveal how compartmentalization of lymphatic drainage to functionally distinct lymph nodes facilitates the simultaneous induction of tolerogenic and effector responses.

Publication types

Comment

MeSH terms

Adaptive Immunity
Drainage*
Intestines
Lymph Nodes*