Ferromagnetic semiconductors exhibit novel spin-dependent optical, electrical, and transport properties, which are promising for next-generation highly functional spintronic devices. However, the possibility of practical applications is hindered by their low Curie temperature. Currently, whether semiconducting ferromagnetism can exist at room temperature is still unclear because of the absence of a solid physical mechanism. Here, on the basis of tight-binding model analysis and first-principles calculations, we report that ferromagnetism in a tetrahedral semiconductor originating from superexchange interactions can be strong enough to survive at room temperature because of the weakening of antiferromagnetic direct-exchange interactions. On the basis of the explored mechanism, a zinc-blende binary transition metal compound, chromium carbide, is predicted to be an intrinsic ferromagnetic tetrahedral semiconductor with a Curie temperature that is as high as ∼1900 K. These findings not only expand the understandings of magnetism in semiconductors but also are of great interest for room-temperature spintronic applications.