A Case of Granulocytic Sarcoma of the Lung in Acute Myeloid Leukemia

Clin Lab. 2019 Jul 1;65(7). doi: 10.7754/Clin.Lab.2018.181239.

Abstract

Background: Granulocytic sarcoma in the lung is a rare presentation of acute myeloid leukemia (AML). Here, we describe a rare case of granulocytic sarcoma of the lung in a 56-year-old male patient with AML.

Methods: Hematologic investigation, bone marrow aspirate, cytogenetic analysis, chest computed tomography (CT), and pulmonary biopsy were performed.

Results: The patient achieved complete remission (CR) after induction therapy, but the patient refused further treatment and was lost to follow-up.

Conclusions: Pulmonary biopsy and bone marrow aspirate are important to confirm a correct diagnosis. Pulmo-nary granulocytic sarcoma as a prognostic factor needs further studies.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Cytarabine / administration & dosage
  • Humans
  • Idarubicin / administration & dosage
  • Induction Chemotherapy
  • Leukemia, Myeloid / complications
  • Leukemia, Myeloid / diagnosis*
  • Leukemia, Myeloid / drug therapy
  • Lung Neoplasms / complications
  • Lung Neoplasms / diagnosis*
  • Lung Neoplasms / drug therapy
  • Male
  • Middle Aged
  • Remission Induction
  • Sarcoma, Myeloid / complications
  • Sarcoma, Myeloid / diagnosis*
  • Sarcoma, Myeloid / drug therapy

Substances

  • Cytarabine
  • Idarubicin