68Ga-DOTATATE Uptake in Pancreatic Metastasis of Renal Cell Carcinoma Mimicking Pancreatic Neuroendocrine Tumor

Clin Nucl Med. 2019 Oct;44(10):795-796. doi: 10.1097/RLU.0000000000002718.

Abstract

A 61-year-old man, with a history of prior clear cell renal cell carcinoma in remission, was referred to Ga-DOTATATE PET/CT for the further evaluation of pancreatic tail mass. Ga-DOTATATE PET/CT showed pathologically intense uptake on the pancreatic mass; subsequent biopsy of the pancreatic mass confirmed the diagnosis of clear cell renal cell carcinoma metastasis. Ga-DOTATATE uptake is not specific for neuroendocrine tumors. In the presence of prior malignancy, it should be kept in mind that malignancies apart from neuroendocrine tumors express somatostatin receptors, and they can show Ga-DOTATATE uptake.

Publication types

  • Case Reports

MeSH terms

  • Biological Transport
  • Carcinoma, Renal Cell / pathology*
  • Humans
  • Kidney Neoplasms / pathology*
  • Male
  • Middle Aged
  • Neuroendocrine Tumors / diagnostic imaging*
  • Neuroendocrine Tumors / metabolism
  • Organometallic Compounds / metabolism*
  • Pancreatic Neoplasms / diagnostic imaging*
  • Pancreatic Neoplasms / metabolism
  • Pancreatic Neoplasms / secondary*
  • Positron Emission Tomography Computed Tomography*
  • Receptors, Somatostatin / metabolism

Substances

  • Organometallic Compounds
  • Receptors, Somatostatin
  • gallium Ga 68 dotatate