Breaking the germline barrier in a moral vacuum

Account Res. 2019 Aug;26(6):351-368. doi: 10.1080/08989621.2019.1644171. Epub 2019 Jul 26.

Abstract

In November 2018 a Chinese scientist claimed to have used CRISPR/Cas 9 technology to genetically modify two human embryos that were then gestated in one adult woman through an IVF pregnancy and brought to term. The twin girls are allegedly the first babies born with their prenatal genomes edited. Using both English language and Chinese supporting documents, this paper discusses the background of this human experiment, the social context of Chinese science, and the alleged ethical transgressions of its principal scientist.

Keywords: AIDS; CCR5; CRISPR/Cas9; HIV; gene editing; human embryos.

MeSH terms

  • CRISPR-Cas Systems*
  • China
  • Embryo Research / ethics*
  • Germ Cells / cytology*
  • HIV Infections / prevention & control
  • Humans
  • Morals*