Some comments on certain statistical aspects of the study of the microbiome

José A Ferreira; Susana Fuentes

doi:10.1093/bib/bbz077

Some comments on certain statistical aspects of the study of the microbiome

Brief Bioinform. 2020 Jul 15;21(4):1487-1494. doi: 10.1093/bib/bbz077.

Authors

José A Ferreira¹, Susana Fuentes²

Affiliations

¹ Department of Statistics and Informatics, RIVM. National Institute for Public Health and the Environment (RIVM). Antonie van Leeuwenhoeklaan 9 3721 MA Bilthoven The Netherlands.
² Centre for Infectious Disease Control, RIVM. National Institute for Public Health and the Environment (RIVM). Antonie van Leeuwenhoeklaan 9 3721 MA Bilthoven The Netherlands.

PMID: 31298267
DOI: 10.1093/bib/bbz077

Abstract

This note complements and clarifies part of the work of Hawinkel et al. recently published in the journal and suggests some more or less standard tools and methods for carrying out association studies of the microbiome.

Keywords: association studies; false discovery rate; microbiome data; nonparametric tests; p-values.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Microbiota*
Models, Statistical*
Publications