High prevalence of eczema among preschool children related to home renovation in China: A multi-city-based cross-sectional study

Indoor Air. 2019 Sep;29(5):748-760. doi: 10.1111/ina.12586. Epub 2019 Jul 11.

Abstract

We surveyed 40 010 three- to six-year-old children in seven Chinese cities (Beijing, Taiyuan, Urumqi, Shanghai, Nanjing, Changsha, and Chongqing) during 2010-2012 so as to investigate possible links between home renovation and childhood eczema. Their parents responded to questions on home renovation and childhood eczema. Multivariate and two-level (city-child) logistic regression analyses yielding odds ratios with 95% confidence intervals were performed. Sensitivity analyses stratifying data for region, climate, and income level were also performed. The prevalences of childhood eczema in children with different floor and wall covering materials were significantly different and were significantly higher with home renovation during early lifetime. Exposure to synthetic materials significantly increased the risk of childhood eczema by 20%-25%. The risks (AOR, 95% CI) of current eczema among children in families with solid wood flooring and oil paint wall covering were 1.25 (1.04-1.49) and 1.35 (1.14-1.60), respectively. Home renovation during pregnancy was related to children's lifetime and current eczema.

Keywords: China; building materials; childhood eczema; home renovation; renovation periods.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Air Pollution, Indoor / adverse effects*
  • Child
  • Child, Preschool
  • China / epidemiology
  • Cities
  • Construction Materials / adverse effects*
  • Cross-Sectional Studies
  • Eczema / epidemiology*
  • Eczema / etiology*
  • Environmental Exposure
  • Female
  • Floors and Floorcoverings
  • Housing
  • Humans
  • Logistic Models
  • Male
  • Paint / adverse effects
  • Pregnancy
  • Prenatal Exposure Delayed Effects / etiology
  • Prevalence
  • Risk Factors
  • Surveys and Questionnaires