The components data of fuzheng huayu extracts, cordyceps sinensis mycelia polysaccharide, gypenosides and amygdalin

Wei Liu; Zhixiong Li; Zhaolin Sun; Yongbin Xu; Shunchun Wang; Yiyang Hu; Jinghua Peng

doi:10.1016/j.dib.2019.104087

The components data of fuzheng huayu extracts, cordyceps sinensis mycelia polysaccharide, gypenosides and amygdalin

Data Brief. 2019 Jun 1:25:104087. doi: 10.1016/j.dib.2019.104087. eCollection 2019 Aug.

Authors

Wei Liu¹, Zhixiong Li², Zhaolin Sun², Yongbin Xu³, Shunchun Wang³, Yiyang Hu^{4

5

6}, Jinghua Peng^{1

5

6}

Affiliations

¹ Institute of Liver Diseases, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
² Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
³ Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
⁴ Institute of Clinical Pharmacology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
⁵ Key Laboratory of Liver and Kidney Diseases (Shanghai University of Traditional Chinese Medicine), Ministry of Education, Shanghai, 201203, China.
⁶ Shanghai Key Laboratory of Traditional Chinese Clinical Medicine, Shanghai, 201203, China.

Abstract

Fuzheng Huayu (FZHY) capsule is a traditional Chinese medicine composed of six Chinese medicinal herbs Tian et al. [1] and approved by China food and drug administration for liver fibrosis treatment [2], [3] Liu et al., 2009 and Liu et al., 2005. CGA formula consisting of Cordyeps sinensis polysaccharide (CS-PS), gypenosides (G), and amygdalin (A), are derived from FZHY formula. It is necessary to identify the chemical profile of FZHY and CGA formula to describe the mechanisms and the corresponding components of anti-fibrosis. It is showed that FZHY contains adenosine (5.21 mg/g), amygdalin (5.31 mg/g), salvianolic acid b (18.22 mg/g) and deoxyschizandrin (2.62 mg/g), respectively. CS-PS contained 60.5 ± 2.2% total carbohydrate, including 14.17% arabinose, 25.35% glucose and 60.48% galactose. Gypenosides contain 10.34% gypenosides XLIX and 16.58% gypenosides A. These data provide the primary chemical profile of FZHY and CGA formula and an example for components analysis of traditional Chinese medicine.

Keywords: Cordyeps sinensis polysaccharide; Fuzheng huayu capsule; Gypenosides; High-performance liquid chromatography; Traditional Chinese medicine.