Associations of apelin, leptin, irisin, ghrelin, insulin, glucose levels, and lipid parameters with physical activity during eight weeks of regular exercise training

Arch Physiol Biochem. 2021 Aug;127(4):291-295. doi: 10.1080/13813455.2019.1635622. Epub 2019 Jul 10.

Abstract

Objectives: This study aims to evaluate the effects of 8 weeks of basketball training on apelin, leptin, irisin, ghrelin, insulin, glucose, and blood lipids among basketball players.

Methods: The exercise groups were given 2 h of basketball training for 5 d a week and for 8 weeks. The control group was randomly selected among the adolescents who did not regularly exercise.

Results: The apelin and ghrelin levels significantly increased; however, leptin, irisin, and insulin levels statistically decreased in the post-exercise group compared to the other groups (p < .05). The results suggest low levels of cholesterol, triglyceride, high-density lipoprotein (HDL), and low-density lipoprotein (LDL) parameters (p < .05).

Conclusions: This study demonstrated that after 8 weeks of chronic exercise training, apelin and ghrelin levels increased; in contrast, leptin, irisin, and insulin levels decreased. The decrease in leptin and irisin levels is compatible with the pattern of decrease in the lipid levels as a result of chronic exercise.

Keywords: Apelin; exercise; ghrelin; glucose; insulin; irisin; leptin; lipid parameters.

MeSH terms

  • Adolescent
  • Apelin / blood*
  • Case-Control Studies
  • Exercise*
  • Fibronectins / blood*
  • Ghrelin / blood*
  • Glucose / analysis*
  • Humans
  • Insulin / blood*
  • Leptin / blood*
  • Lipids / blood*
  • Male
  • Time Factors

Substances

  • Apelin
  • FNDC5 protein, human
  • Fibronectins
  • Ghrelin
  • Insulin
  • Leptin
  • Lipids
  • Glucose