Dietary intake and micronutrient deficiency in children with cancer

Pediatr Blood Cancer. 2019 Oct;66(10):e27895. doi: 10.1002/pbc.27895. Epub 2019 Jul 9.

Abstract

Data regarding micronutrient deficiencies in children with cancer are lacking. We measured micronutrients in a subset of children with cancer (n = 23) participating in a randomized trial of the neutropenic diet. Ninety-six percent of children had ≥1 micronutrient deficiency and 39% had ≥3 micronutrient deficiencies. Eighty-six percent of children had vitamin C deficiency, 87% had 25-hydroxyvitamin D deficiency, 50% had zinc deficiency, and 13% had vitamin A deficiency. Dietary intake did not correlate with micronutrient deficiency status. More data are needed regarding the prevalence and etiology of micronutrient deficiencies in children with cancer to further understand their implications and treatment.

Keywords: macronutrients; micronutrients; nutritional deficiency; nutritional support; pediatric oncology; quality of life; support care; vitamins.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Diet*
  • Female
  • Humans
  • Infant
  • Male
  • Micronutrients / deficiency*
  • Neoplasms*
  • Nutritional Status
  • Prevalence
  • Randomized Controlled Trials as Topic
  • Retrospective Studies

Substances

  • Micronutrients