Abscisic acid identification in Okra, Abelmoschus esculentus L. (Moench): perspective nutraceutical use for the treatment of diabetes

Nat Prod Res. 2020 Jan;34(1):3-9. doi: 10.1080/14786419.2019.1637874. Epub 2019 Jul 8.

Abstract

Okra, Abelmoschus esculentus L. (Moench), also known as Lady's Fingers, gombo, or bamje, is an annual plant belonging to the Malvaceae family. Traditional olistic medicine since centuries directly associates this plant and its parts to a beneficial health hypoglycemic effect. Since the abscisic acid (ABA) has been associated to an interesting hypoglycemic effect, this triggered us to verify and quantify the presence of the abscisic acid in the okra phytocomplex. In particular, ABA, a plant derived hormone, has been proven by recent studies to be effective on mammals. To determine and quantify the ABA content, different parts of the Okra plant extracts have been evaluated, and HPLC-DAD analysis has been used allowing us to report for the first time the presence of this isoprenoid compound. Bioaccessibility has been also investigated using a simulated gastro intestinal (GI) digestion protocol with the aim of explore the possibility of okra extract as nutraceutical.

Keywords: abscisic acid; bioaccessibility; diabetes; nutraceutical; okra; phytocomplex.

MeSH terms

  • Abelmoschus / chemistry*
  • Abscisic Acid / analysis*
  • Chromatography, High Pressure Liquid
  • Diabetes Mellitus / drug therapy*
  • Dietary Supplements
  • Hypoglycemic Agents / analysis
  • Hypoglycemic Agents / isolation & purification
  • Hypoglycemic Agents / pharmacology
  • Malvaceae
  • Plant Extracts / chemistry*

Substances

  • Hypoglycemic Agents
  • Plant Extracts
  • Abscisic Acid