Water-soluble conjugated polymer with near-infrared absorption for synergistic tumor therapy using photothermal and photodynamic activity

Sirong Zhou; Changgang Yang; Lixia Guo; Yunxia Wang; Guofeng Zhang; Liheng Feng

doi:10.1039/c9cc03744f

Water-soluble conjugated polymer with near-infrared absorption for synergistic tumor therapy using photothermal and photodynamic activity

Chem Commun (Camb). 2019 Jul 18;55(59):8615-8618. doi: 10.1039/c9cc03744f.

Authors

Sirong Zhou¹, Changgang Yang², Lixia Guo¹, Yunxia Wang¹, Guofeng Zhang², Liheng Feng¹

Affiliations

¹ School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan, 030006, P. R. China. lhfeng@sxu.edu.cn wangyunxia@sxu.edu.cn.
² State Key Laboratory of Quantum Optics and Quantum Optics Devices, Institute of Laser Spectroscopy, Shanxi University, Taiyuan, 030006, P. R. China. guofeng.zhang@sxu.edu.cn.

PMID: 31281904
DOI: 10.1039/c9cc03744f

Abstract

A novel near-infrared absorbing photo-agent based on a water-soluble conjugated polymer (PTDBD) is reported for synergetic photothermal/photodynamic therapy with single near-infrared light (808 nm) irradiation. In vitro and in vivo studies demonstrated the superior therapeutic effect of the single NIR-irradiated PTT/PDT by using PTDBD.