Management of acute variceal hemorrhage

F1000Res. 2019 Jun 25:8:F1000 Faculty Rev-966. doi: 10.12688/f1000research.18807.1. eCollection 2019.

Abstract

Gastrointestinal bleeding is one of the major causes of death in patients with cirrhosis, and gastroesophageal varices represent the main source of hemorrhage. Even though in the last decades survival has been improved because of the widespread adoption of effective treatments and optimization of general medical care, mortality is still significantly high, and decompensated patients pose a complex challenge requiring a multidisciplinary approach that is crucial to improve survival. The aims of this commentary are to review the most recent advances in the management of esophageal variceal bleeding and to highlight useful information to aid hepatologists in clinical practice.

Keywords: TIPS; cirrhosis; non-selective betablockers; portal hypertension; variceal bleeding.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Acute Disease
  • Esophageal and Gastric Varices* / complications
  • Gastrointestinal Hemorrhage* / etiology
  • Gastrointestinal Hemorrhage* / therapy
  • Humans
  • Hypertension, Portal* / complications
  • Liver Cirrhosis