Fasting blood glucose level and hypertension risk in aging benign prostatic hyperplasia patients

Aging (Albany NY). 2019 Jul 3;11(13):4438-4445. doi: 10.18632/aging.102061.

Abstract

Evidence suggests there maybe an association among abnormal fasting blood glucose, hypertension and benign prostatic hyperplasia. In this study, we investigated whether abnormal fasting blood glucose correlates with hypertension in aging benign prostatic hyperplasia patients. Ultimately, 612 benign prostatic hyperplasia patients, including 230 hypertensive patients and 382 normotensive patients, were included. Univariate and multivariate logistic regression analyses were used to evaluate the associations. The results indicated that neither impaired fasting glucose/high risk of type 2 diabetes mellitus nor high risk of type 2 diabetes mellitus were associated with an increased risk of hypertension. When patients were stratified based on the severity of their hypertension, similar results were obtained (all P> 0.05). After adjusting for confounding factors, the nonsignificant tendencies for high risk of type 2 diabetes mellitus and impaired fasting glucose/high risk of type 2 diabetes mellitus to associate with hypertension persisted (all P> 0.05). Unlike earlier studies, the present study suggests that the level of fasting blood glucose may not be significantly related to hypertension in aging patients with benign prostatic hyperplasia.

Keywords: blood glucose; diabetes mellitus; hypertension; prostatic hyperplasia; type 2.

Publication types

  • Observational Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Blood Glucose*
  • Humans
  • Hypertension / blood
  • Hypertension / complications*
  • Male
  • Middle Aged
  • Prostatic Hyperplasia / blood
  • Prostatic Hyperplasia / complications*
  • Retrospective Studies

Substances

  • Blood Glucose