The Role of Cardiac MR Imaging in the Assessment of Patients with Cardiac Amyloidosis

Filipe Penna de Carvalho; Fernanda Erthal; Clerio F Azevedo

doi:10.1016/j.mric.2019.04.005

The Role of Cardiac MR Imaging in the Assessment of Patients with Cardiac Amyloidosis

Magn Reson Imaging Clin N Am. 2019 Aug;27(3):453-463. doi: 10.1016/j.mric.2019.04.005. Epub 2019 May 9.

Authors

Filipe Penna de Carvalho¹, Fernanda Erthal¹, Clerio F Azevedo²

Affiliations

¹ Diagnósticos da America (DASA), Unidade CID Leblon, Av. Ataulfo de Paiva 669, CEP 22440-032, Rio de Janeiro, RJ, Brazil.
² Diagnósticos da America (DASA), Unidade CID Leblon, Av. Ataulfo de Paiva 669, CEP 22440-032, Rio de Janeiro, RJ, Brazil; Division of Cardiology, Duke University Medical Center, Duke Medical Pavilion, 10 Medicine Circle, Room 1E63, DUMC 3934, Durham, NC 27710, USA. Electronic address: clerio.azevedo@duke.edu.

PMID: 31279449
DOI: 10.1016/j.mric.2019.04.005

Abstract

Despite recent advancements in newer biomarkers development and improved imaging techniques, the diagnosis of cardiac amyloidosis (CA) remains a frequent clinical challenge. In this setting, cardiac MR (CMR) imaging has emerged as a powerful tool to assess heart morphology and function, with the unique advantage of noninvasive tissue characterization. This article summarizes the CMR imaging common findings in CA and the latest research in this field, including delayed enhancement, native T1 mapping, and extracellular volume quantification.

Keywords: Amyloidosis; Cardiac MR; Delayed enhancement; Extracellular volume fraction; T1 mapping.

Publication types

Review

MeSH terms

Amyloidosis / diagnostic imaging*
Heart / diagnostic imaging
Heart Diseases / diagnostic imaging*
Humans
Magnetic Resonance Imaging / methods*