Antimicrobial peptide derived from insulin-like growth factor-binding protein 5 activates mast cells via Mas-related G protein-coupled receptor X2

Allergy. 2020 Jan;75(1):203-207. doi: 10.1111/all.13975. Epub 2019 Jul 28.
No abstract available

Keywords: MAPK/NF-κB; Mas-related G protein-coupled receptor X; antimicrobial peptide; mast cell; wound healing.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Degranulation / immunology*
  • Cell Line
  • Humans
  • Insulin-Like Growth Factor Binding Protein 5 / immunology*
  • Insulin-Like Growth Factor Binding Protein 5 / metabolism
  • Mast Cells / immunology*
  • Mast Cells / metabolism
  • Nerve Tissue Proteins / immunology*
  • Nerve Tissue Proteins / metabolism
  • Pore Forming Cytotoxic Proteins / immunology*
  • Pore Forming Cytotoxic Proteins / metabolism
  • Receptors, G-Protein-Coupled / immunology*
  • Receptors, G-Protein-Coupled / metabolism
  • Receptors, Neuropeptide / immunology*
  • Receptors, Neuropeptide / metabolism

Substances

  • IGFBP5 protein, human
  • Insulin-Like Growth Factor Binding Protein 5
  • MRGPRX2 protein, human
  • Nerve Tissue Proteins
  • Pore Forming Cytotoxic Proteins
  • Receptors, G-Protein-Coupled
  • Receptors, Neuropeptide