Structure and antimicrobial properties of long-chain branched poly (lactic acid)

J Biomed Mater Res A. 2019 Nov;107(11):2458-2467. doi: 10.1002/jbm.a.36752. Epub 2019 Jul 12.

Abstract

Long-chain branched poly (lactic acid) (LCB-PLA) with antimicrobial functional group was fabricated through a two-step ring-opening reactive processing for improving antimicrobial properties and broadening the PLA processing window. A combination of linear viscoelasticity and the branch-on-branch (BOB) model predicted probable compositions and chain topologies of the products. It is also explored the antimicrobial properties of LCB-PLA to provide a theoretical basis for broadening the possible applications.

Keywords: antimicrobial properties; long-chain branched structure; poly lactic acid (PLA).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Infective Agents / chemical synthesis*
  • Anti-Infective Agents / chemistry*
  • Polyesters / chemical synthesis*
  • Polyesters / chemistry*
  • Structure-Activity Relationship

Substances

  • Anti-Infective Agents
  • Polyesters
  • poly(lactide)