Leukocytoclastic Vasculitis Related to Ustekinumab in a Crohn's Disease Patient: First Case Report and Literature Review

J Crohns Colitis. 2020 Feb 10;14(2):274-276. doi: 10.1093/ecco-jcc/jjz128.

Abstract

Leukocytoclastic vasculitis is a single-organ, skin-isolated small vessel vasculitis. It can be a side effect of many common drugs, including biological agents. Unlike with other drugs, leukocytoclastic vasculitis induced by biological agents may have a prolonged latency period. We report the first case of ustekinumab-induced leukocytoclastic vasculitis in a patient with inflammatory bowel disease.

Keywords: Crohn’s disease; Leukocytoclastic vasculitis; ustekinumab.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Crohn Disease / drug therapy*
  • Female
  • Gastrointestinal Agents / adverse effects*
  • Gastrointestinal Agents / therapeutic use
  • Humans
  • Leg
  • Skin / pathology
  • Ustekinumab / adverse effects*
  • Ustekinumab / therapeutic use
  • Vasculitis, Leukocytoclastic, Cutaneous / chemically induced*
  • Vasculitis, Leukocytoclastic, Cutaneous / pathology
  • Wit and Humor as Topic

Substances

  • Gastrointestinal Agents
  • Ustekinumab