Removing One Barrier to Protecting Sex Partners in HIV Remission Studies With a Treatment Interruption

J Infect Dis. 2019 Jul 2;220(220 Suppl 1):S22-S23. doi: 10.1093/infdis/jiz162.

Abstract

Only a few of the recommendations made in this supplement are implemented in ongoing HIV remission studies that involve an analytical treatment interruption. The absence of these recommendations in protocols puts sexual partners of study participants at serious risk. This paper addresses one possible barrier to implementation: a certain misunderstanding among sponsors and research entities.

Keywords: HIV; HIV cure-related studies; analytic treatment interruption; clinical trials; human subject research; research ethics.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Anti-HIV Agents / administration & dosage*
  • Coinfection / prevention & control*
  • Female
  • HIV Infections / prevention & control*
  • HIV Infections / transmission*
  • Humans
  • Male
  • Remission Induction
  • Risk Factors
  • Sexual Partners / psychology*
  • United States
  • Unsafe Sex / prevention & control*
  • Vaccines / administration & dosage*
  • Withholding Treatment

Substances

  • Anti-HIV Agents
  • Vaccines