Addition of 2-deoxy-d-ribose to clinically used alginate dressings stimulates angiogenesis and accelerates wound healing in diabetic rats

J Biomater Appl. 2019 Oct;34(4):463-475. doi: 10.1177/0885328219859991. Epub 2019 Jul 1.

Authors

Maryam Azam¹, Serkan Dikici², Sabiniano Roman², Azra Mehmood³, Aqif A Chaudhry¹, Ihtesham U Rehman⁴, Sheila MacNeil², Muhammad Yar¹

Affiliations

¹ 1 Interdisciplinary Research Centre in Biomedical Materials (IRCBM), COMSATS University Islamabad Lahore Campus, Lahore, Pakistan.
² 2 Department of Materials Science & Engineering, Kroto Research Institute, University of Sheffield, UK.
³ 3 Center of Excellence in Molecular Biology (CEMB), University of the Punjab, Lahore, Pakistan.
⁴ 4 Engineering Department, Lancaster University, UK.

PMID: 31262210
DOI: 10.1177/0885328219859991

No abstract available

Keywords: 2-Deoxy--ribose; CD34; angiogenesis; diabetic wounds; immunohistochemistry.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alginates / therapeutic use*
Angiogenesis Inducing Agents / therapeutic use*
Animals
Bandages
Deoxyribose / therapeutic use*
Diabetes Mellitus, Experimental / complications*
Diabetes Mellitus, Experimental / pathology
Male
Neovascularization, Physiologic / drug effects
Rats
Rats, Wistar
Wound Healing / drug effects*

Substances

Alginates
Angiogenesis Inducing Agents
Deoxyribose