Gender differences in aphasia outcomes: evidence from the AphasiaBank

Int J Lang Commun Disord. 2019 Sep;54(5):806-813. doi: 10.1111/1460-6984.12486. Epub 2019 Jun 30.

Abstract

Background: Stroke is one of the leading causes of death in the United States. Aphasia is a language impairment which results as a consequence of stroke. Gender differences are reported in underlying mechanisms of stroke, however, gender differences in aphasia type and severity remain unclear.

Aims: To examine gender differences in aphasia impairment based on data from AphasiaBank, a research repository of data obtained from studies of aphasia.

Methods & procedures: The data were collected from AphasiaBank for 294 persons with aphasia (PWA) (172 men, 122 women). Baseline comparisons by gender groups were completed using independent samples t-tests and Pearson Chi square statistics. Univariate comparisons of the total Western Aphasia Battery-Revised (WAB-R) -AQ and -R subtests' scores were compared between the two groups using independent samples t-tests. Multivariate comparisons were completed by using multivariate analysis of variance (MANOVA).

Outcomes & results: Gender differences were observed in the severity of aphasia with men exhibiting more severe aphasia than women. Analyses of WAB-R indicated greater impairment among men based on AQ and greater impairment was observed in individual subtest performance. Men exhibited statistically significantly lower WAB-R AQs than women (67.4 versus 75.6). Lower WAB-R AQs were derived from lower scores among men on individual subtests; information content, fluency, repetition, sentence completion, responsive speech and tests of comprehension (yes/no, auditory word recognition and sequential commands).

Conclusions & implications: This study offers evidence of gender differences in aphasia severity, global communication impairment and lower scores on individual subtests used to derive the WAB-R AQ. The limitations of the study with suggestions for future directions are presented.

Keywords: aphasia outcomes; aphasia severity; gender differences; persons with aphasia; stroke.

MeSH terms

  • Aged
  • Aphasia / diagnosis
  • Aphasia / etiology*
  • Databases, Factual
  • Evidence-Based Medicine / methods
  • Female
  • Humans
  • Language Tests
  • Male
  • Middle Aged
  • Neuropsychological Tests
  • Prognosis
  • Retrospective Studies
  • Severity of Illness Index
  • Sex Factors
  • Stroke / complications*