Tocopherols, tocotrienols and tocomonoenols: Many similar molecules but only one vitamin E

Redox Biol. 2019 Sep:26:101259. doi: 10.1016/j.redox.2019.101259. Epub 2019 Jun 19.

Abstract

The aim of this article is to correct a very general error in scientific articles, in textbooks and in the Internet that has become an accepted fact. In this literature, the term "vitamin E″ is used for several similar molecules (both tocopherols and tocotrienols) that have never been shown to have vitamin property, i.e. a protective effect against the human deficiency disease. In fact, the name "vitamin E″ should only be used to define molecules that prevent the human deficiency disease "Ataxia with Vitamin E Deficiency" (AVED). Only one such molecule is known, α-tocopherol. This error may confuse consumers as well as medical doctors, who prescribe vitamin E without realizing that the current use of the name includes molecules of unknown, if not unwanted functions.

Publication types

  • Review

MeSH terms

  • Antioxidants / administration & dosage*
  • Ascorbic Acid / administration & dosage
  • Ataxia / diet therapy*
  • Ataxia / metabolism
  • Ataxia / physiopathology
  • Ataxia / prevention & control
  • Calcitriol / administration & dosage
  • Dietary Supplements*
  • Humans
  • Rickets / diet therapy*
  • Rickets / metabolism
  • Rickets / physiopathology
  • Rickets / prevention & control
  • Scurvy / diet therapy*
  • Scurvy / metabolism
  • Scurvy / physiopathology
  • Scurvy / prevention & control
  • Stereoisomerism
  • Terminology as Topic
  • Tocotrienols / chemistry
  • Tocotrienols / classification
  • Vitamin E / administration & dosage
  • Vitamin E Deficiency / diet therapy*
  • Vitamin E Deficiency / metabolism
  • Vitamin E Deficiency / physiopathology
  • Vitamin E Deficiency / prevention & control
  • alpha-Tocopherol / administration & dosage

Substances

  • Antioxidants
  • Tocotrienols
  • Vitamin E
  • Calcitriol
  • alpha-Tocopherol
  • Ascorbic Acid

Supplementary concepts

  • Ataxia with vitamin E deficiency