Microscopic Colitis Is Characterized by Intestinal Dysbiosis

Abstract

The critical role of the gut microbiome in microscopic colitis (MC) is evident by the observation that fecal diversion is associated with resolution of mucosal inflammation while restoration of fecal stream is associated with recurrence of disease.¹ Characterization of the composition and function of the gut microbiome in MC therefore could provide insights into disease pathogenesis.