Low 68Ga-PSMA PET/CT Uptake in Chronic Intramuscular Nodular Fasciitis

Clin Nucl Med. 2020 Jan;45(1):e41-e42. doi: 10.1097/RLU.0000000000002675.

Abstract

Nodular fasciitis is an uncommon benign mass-forming myofibroblastic proliferation, most frequently found in the upper limbs, with only rare intramuscular cases. We describe herein a case of chronic nodular fasciitis of the left triceps muscle with a low Ga-labeled prostate-specific membrane antigen (PSMA) ligand uptake on PET/CT. Ga-PSMA ligands bind to PSMA-expressing prostate cancer cells, but uptake has also been demonstrated in other solid neoplasms and various benign lesions. Nodular fasciitis should be included in the differential diagnosis of soft tissue lesions with variable Ga-PSMA uptake.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biological Transport
  • Chronic Disease
  • Diagnosis, Differential
  • Fasciitis / diagnosis*
  • Fasciitis / metabolism*
  • Gallium Isotopes
  • Gallium Radioisotopes
  • Humans
  • Male
  • Membrane Glycoproteins / metabolism*
  • Muscles / diagnostic imaging*
  • Organometallic Compounds / metabolism*
  • Positron Emission Tomography Computed Tomography*
  • Prostatic Neoplasms / pathology

Substances

  • Gallium Isotopes
  • Gallium Radioisotopes
  • Membrane Glycoproteins
  • Organometallic Compounds
  • gallium 68 PSMA-11