Severe Eosinophilic Meningoencephalitis Secondary to Suspected Neuroangiostrongyliasis with a Good Clinical Outcome

Fabian Chiong; Andrew R Lloyd; Jeffrey J Post

doi:10.1155/2019/4037196

Severe Eosinophilic Meningoencephalitis Secondary to Suspected Neuroangiostrongyliasis with a Good Clinical Outcome

Case Rep Infect Dis. 2019 May 26:2019:4037196. doi: 10.1155/2019/4037196. eCollection 2019.

Authors

Fabian Chiong^{1

2}, Andrew R Lloyd^{1

3}, Jeffrey J Post^{1

2}

Affiliations

¹ Department of Infectious Diseases, Prince of Wales Hospital, Sydney, NSW, Australia.
² Prince of Wales Clinical School, University of New South Wales, Sydney, NSW, Australia.
³ Kirby Institute, University of New South Wales, Sydney, NSW, Australia.

Abstract

Angiostrongylus cantonensis has caused sporadic cases of eosinophilic meningoencephalitis in Sydney, Australia. We describe a 36-year-old man who presented subacutely with fevers, reduced level of consciousness, confusion, ophthalmoplegia, and urinary incontinence. He was diagnosed with severe eosinophilic meningoencephalitis secondary to suspected Angiostrongylus cantonensis based on clinical, serological, and radiological findings. The patient was treated with albendazole and prednisolone with full neurological recovery. Management of neuroangiostrongyliasis with anthelminthic is controversial as it is thought to cause worsened outcomes through inciting an inflammatory response as a result of parasite killing. We managed to successfully treat our patient using albendazole and prednisolone and achieved a good outcome.

Publication types

Case Reports