Genomic Analysis and Treatment Response of a Bladder Urothelial Carcinoma With Sarcomatoid Variant Histology

Clin Genitourin Cancer. 2019 Oct;17(5):e888-e892. doi: 10.1016/j.clgc.2019.05.019. Epub 2019 May 25.
No abstract available

Keywords: Bladder cancer; Case report; EMT transformation; Genomic subtyping; Histologic variant.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antibodies, Monoclonal, Humanized / therapeutic use*
  • B7-H1 Antigen / genetics
  • Carcinoma, Renal Cell / drug therapy*
  • Carcinoma, Renal Cell / genetics
  • Carcinoma, Transitional Cell / drug therapy*
  • Carcinoma, Transitional Cell / genetics
  • Epithelial-Mesenchymal Transition
  • Female
  • Genomics
  • Humans
  • Neoadjuvant Therapy
  • Neoplasm Invasiveness
  • Programmed Cell Death 1 Ligand 2 Protein / genetics
  • Treatment Outcome
  • Up-Regulation
  • Urinary Bladder Neoplasms / drug therapy*
  • Urinary Bladder Neoplasms / genetics

Substances

  • Antibodies, Monoclonal, Humanized
  • B7-H1 Antigen
  • CD274 protein, human
  • PDCD1LG2 protein, human
  • Programmed Cell Death 1 Ligand 2 Protein
  • pembrolizumab