Radiofrequency Ablation of Facial Venolymphatic Malformations: Assessment of Efficacy and Safety and the Role of Injectable Electrodes

J Vasc Interv Radiol. 2020 Apr;31(4):544-550. doi: 10.1016/j.jvir.2019.04.006. Epub 2019 Jun 22.

Abstract

Purpose: To evaluate the efficacy and safety of ultrasound (US)-guided radiofrequency (RF) ablation in the treatment of facial microcystic lymphatic malformations (mLMs) or mixed venolymphatic malformations (VLMs) and to introduce the "induced-paralysis" technique with the use of an injectable electrode to minimize neural complications.

Materials and methods: Data from patients with symptomatic facial mLMs or mixed VLMs who underwent US-guided RF ablation in 2014-2017 were retrospectively reviewed. Computed tomography (CT) and/or magnetic resonance (MR) imaging was used to localize any functional structures close to the target lesion. Treatment outcome was assessed by 4-point cosmetic grading score (CGS). Treatment outcome was compared between patients with vs without a functional structure close to the lesion and those treated with a noninjectable vs an injectable electrode. Immediate and late complications were assessed during follow-up.

Results: Data from 15 patients were evaluated. Initial CGS and median volume were significantly decreased at the last follow-up in all patients (from 4 to 1 and from 7 mL to 0.7 mL, respectively; P < .05). Treatment outcome differed significantly between those with and without a functional structure on CT or MR imaging (P < .05) but showed no difference between noninjectable (n = 9) and injectable electrodes (n = 6). Two cases of transient cranial nerve palsy were seen in the noninjectable electrode group.

Conclusions: US-guided RF ablation is effective in patients with facial mLMs or mixed VLMs. The induced-paralysis technique with an injectable electrode has the potential to ensure technical safety without compromising efficacy.

Publication types

  • Video-Audio Media

MeSH terms

  • Adolescent
  • Adult
  • Catheter Ablation / adverse effects
  • Catheter Ablation / instrumentation*
  • Cranial Nerve Diseases / etiology
  • Electrodes*
  • Female
  • Humans
  • Lymphatic Abnormalities / diagnostic imaging
  • Lymphatic Abnormalities / surgery*
  • Lymphatic Vessels / abnormalities
  • Lymphatic Vessels / diagnostic imaging
  • Lymphatic Vessels / surgery*
  • Male
  • Middle Aged
  • Patient Safety
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors
  • Time Factors
  • Treatment Outcome
  • Ultrasonography, Interventional
  • Vascular Malformations / diagnostic imaging
  • Vascular Malformations / surgery*
  • Veins / abnormalities
  • Veins / diagnostic imaging
  • Veins / surgery*
  • Young Adult