VanA-type vancomycin-resistant Enterococcus faecium ST1336 isolated from mussels in an anthropogenically impacted ecosystem

Andrey G Sacramento; Miriam R Fernandes; Fábio P Sellera; Silvio S Dolabella; Rosemeire C Zanella; Louise Cerdeira; Nilton Lincopan

doi:10.1016/j.marpolbul.2019.04.014

VanA-type vancomycin-resistant Enterococcus faecium ST1336 isolated from mussels in an anthropogenically impacted ecosystem

Mar Pollut Bull. 2019 May:142:533-536. doi: 10.1016/j.marpolbul.2019.04.014. Epub 2019 Apr 9.

Authors

Andrey G Sacramento¹, Miriam R Fernandes², Fábio P Sellera³, Silvio S Dolabella⁴, Rosemeire C Zanella⁵, Louise Cerdeira², Nilton Lincopan⁶

Affiliations

¹ Department of Morphology, Federal University of Sergipe, São Cristóvão, Brazil. Electronic address: sacramento@usp.br.
² Department of Clinical Analysis, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.
³ Department of Internal Medicine, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, Brazil.
⁴ Department of Morphology, Federal University of Sergipe, São Cristóvão, Brazil.
⁵ Bacteriology Branch, Instituto Adolfo Lutz, São Paulo, Brazil.
⁶ Department of Clinical Analysis, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil. Electronic address: lincopan@usp.br.

PMID: 31232334
DOI: 10.1016/j.marpolbul.2019.04.014

Abstract

We report the occurrence and genomic features of multidrug-resistant vancomycin-resistant Enterococcus faecium vanA belonging to a novel sequence type (designated ST1336), carrying a Tn1546-like element, in marine brown mussels (Perna perna) from anthropogenically affected coastal waters of the Atlantic coast of Brazil, highlighting a potential source of dissemination for related ecosystems, with additional consequences for seafood safety and quality.

Keywords: Bivalve; Brazil; E. faecium; Marine pollution; Seafood; VRE.

MeSH terms

Animals
Bacterial Proteins / genetics
Brazil
Carbon-Oxygen Ligases / genetics
DNA Transposable Elements
Ecosystem
Enterococcus faecium / drug effects*
Enterococcus faecium / genetics
Enterococcus faecium / isolation & purification*
Humans
Microbial Sensitivity Tests
Perna / microbiology*
Vancomycin Resistance / genetics*

Substances

Bacterial Proteins
DNA Transposable Elements
VanA ligase, Bacteria
Carbon-Oxygen Ligases