Nanomaterials for tumor immunomodulation and overcoming current clinical challenges

Samaresh Sau; Rami Alzhrani; Ketki Bhise; Hashem O Alsaab; Sushil K Kashaw; Arun K Iyer

doi:10.2217/nnm-2019-0109

Nanomaterials for tumor immunomodulation and overcoming current clinical challenges

Nanomedicine (Lond). 2019 Jun;14(12):1515-1519. doi: 10.2217/nnm-2019-0109. Epub 2019 Jun 24.

Authors

Samaresh Sau¹, Rami Alzhrani^{1

2}, Ketki Bhise¹, Hashem O Alsaab^{1

2}, Sushil K Kashaw³, Arun K Iyer^{1

4}

Affiliations

¹ Use-inspired Biomaterials & Integrated Nano Delivery (U-BiND) Systems Laboratory, Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy & Health Sciences, Wayne State University, Detroit, MI 48201, USA.
² Department of Pharmaceutics & Pharmaceutical Technology, College of Pharmacy, Taif University, Taif, 25671, Saudi Arabia.
³ Department of Pharmaceutical Sciences, Dr Harisingh Gour University (A Central University), Sagar, MP, India.
⁴ Molecular Imaging Program, Barbara Ann Karmanos Cancer Institute, Wayne State University, School of Medicine, Detroit, MI 48201, USA.

PMID: 31232169
DOI: 10.2217/nnm-2019-0109

No abstract available

Keywords: CTLA-4; PD-1; PDL-1; cancer vaccine; clinical barrier and safety of nanomedicine; immunotherapy; reproducibility of nanoparticle synthesis.

MeSH terms

Animals
Humans
Immunomodulation / physiology
Immunotherapy / methods*
Nanomedicine / methods*
Nanostructures / chemistry*