Corollary Discharge Signals in the Cerebellum

Abstract

The cerebellum is known to make movements fast, smooth, and accurate. Many hypotheses emphasize the role of the cerebellum in computing learned predictions important for sensorimotor calibration and feedforward control of movements. Hypotheses of the computations performed by the cerebellum in service of motor control borrow heavily from control systems theory, with models that frequently invoke copies of motor commands, called corollary discharge. This review describes evidence for corollary discharge inputs to the cerebellum and highlights the hypothesized roles for this information in cerebellar motor-related computations. Insights into the role of corollary discharge in motor control, described here, are intended to inform the exciting but still untested roles of corollary discharge in cognition, perception, and thought control relevant in psychiatric disorders.

Keywords: Cerebellar; Corollary discharge; Efference copy; Mossy fibers; Motor control; Reafference.