Hailey-Hailey disease: the role of azathioprine an immunomodulator

Pan Afr Med J. 2019 Feb 5:32:65. doi: 10.11604/pamj.2019.32.65.17877. eCollection 2019.

Abstract

Hailey-Hailey disease (HHD) is a rare autosomal dominant hereditary blistering and erosions disorder affecting the intertriginous regions of the body. There is still no treatment protocol for this disease thus clinicians are highly advised to draw up individualized treatment plan. In this case report, we discuss a case of HHD in a 58-year-old Chinese man who was successfully treated with azathioprine in Hubei province.

Keywords: Familial benign chronic pemphigus; Hailey-Hailey disease; azathioprine; benign chronic familial pemphigus; benign chronic pemphigus; familial benign pemphigus.

Publication types

  • Case Reports

MeSH terms

  • Azathioprine / therapeutic use*
  • Humans
  • Immunologic Factors / therapeutic use*
  • Male
  • Middle Aged
  • Pemphigus, Benign Familial / drug therapy*
  • Pemphigus, Benign Familial / physiopathology
  • Treatment Outcome

Substances

  • Immunologic Factors
  • Azathioprine