Investigating Outcomes of Adolescents and Young Adults (10-24 Years of Age) Lost to Follow-up from Tuberculosis Treatment in Gaborone, Botswana

Leslie A Enane; Elizabeth D Lowenthal; Tonya Arscott-Mills; Jessica Eby; Cynthia Caiphus; Botshelo Kgwaadira; Susan E Coffin; Andrew P Steenhoff

doi:10.1097/INF.0000000000002369

Investigating Outcomes of Adolescents and Young Adults (10-24 Years of Age) Lost to Follow-up from Tuberculosis Treatment in Gaborone, Botswana

Pediatr Infect Dis J. 2019 Oct;38(10):e271-e274. doi: 10.1097/INF.0000000000002369.

Authors

Leslie A Enane^{1

2

3

4}, Elizabeth D Lowenthal^{2

4

5}, Tonya Arscott-Mills^{2

4

6}, Jessica Eby⁶, Cynthia Caiphus⁷, Botshelo Kgwaadira^{6

7}, Susan E Coffin^{1

2

6}, Andrew P Steenhoff^{1

2

4

6}

Affiliations

¹ From the Division of Infectious Diseases, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
² Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
³ The Ryan White Center for Pediatric Infectious Disease and Global Health, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana.
⁴ Botswana-UPenn Partnership, Gaborone, Botswana.
⁵ Center for Clinical Epidemiology & Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
⁶ University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
⁷ Botswana National TB Program, Ministry of Health, Gaborone, Botswana.

Abstract

This retrospective study investigated outcomes among lost to follow-up (LTFU) adolescents and young adults (AYAs: 10-24 years of age) with tuberculosis (TB) registered from 2008 to 2014 in Gaborone, using surveillance data. Of 68 LTFU AYAs, 16 repeated treatment; 8 completed and 6 were again LTFU. Of 4 confirmed deaths, 3 had TB/HIV coinfection. Approaches to improve AYA retention in TB care are needed.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Botswana
Child
Female
Humans
Lost to Follow-Up*
Male
Retrospective Studies
Treatment Outcome
Tuberculosis / drug therapy*
Young Adult

Abstract

Publication types

MeSH terms

Grants and funding