Analysis of survival for lung cancer resections cases with fuzzy and soft set theory in surgical decision making

PLoS One. 2019 Jun 19;14(6):e0218283. doi: 10.1371/journal.pone.0218283. eCollection 2019.

Abstract

Objective: Lung cancer is the most common type of cancer around the world, and it represents the main cause of death in the USA. Surgical treatment is the optimal therapeutic strategy for resectable non-small cell lung cancer. The principal factor for long-term survival after complete resection is the anatomic extension of the neoplasm. However, other factors also have adverse effects on operative mortality, and influence long-term outcome. In this paper we propose an algorithmic solution for the estimation of 5-years survival rate in lung cancer patients undertaking pulmonary resection.

Materials and methods: We address the issue of survival analysis through decision-making techniques based on fuzzy and soft set theories. We develop an expert system based on clinical and functional data of lung cancer resections in patients with cancer that can be used to predict the survival of patients.

Results: The evaluation of surgical risk in patients undertaking pulmonary resection is a primary target for thoracic surgeons. Lung cancer survival is influenced by many factors. The computational performance of our algorithm is critically analyzed by an experimental study. The correct survival classification is achieved with an accuracy of 79.0%. Our novel soft-set based criterion is an effective and precise diagnosis application for the determination of the survival rate.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Cancer Survivors*
  • Decision Making
  • Female
  • Humans
  • Lung / pathology
  • Lung / surgery*
  • Lung Neoplasms / epidemiology*
  • Lung Neoplasms / pathology
  • Lung Neoplasms / surgery
  • Lymph Node Excision / methods
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Pneumonectomy
  • Survival Analysis*

Grants and funding

This research was funded by Ministerio de Economía, Industria y Competitividad, Gobierno de España (TIN2015-67522-C3-3-R to GS-G), and Secretaría de Estado de Investigación, Desarrollo e Innovación (TIN2012-39391-C04-04 to GS-G). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.