Abstract
We studied the clinical and epidemiologic features of an outbreak of Crimean-Congo hemorrhagic fever in Herat Province, Afghanistan. The study comprised 63 patients hospitalized in 2017. The overall case-fatality rate was 22.2%; fatal outcome was significantly associated with a negative IgM test result, longer prothrombin time, and nausea.
Keywords:
Afghanistan; CCHF; CCHFV; Crimean-Congo hemorrhagic fever; Crimean-Congo hemorrhagic fever virus; clinical symptomatology; epidemiology; ticks; vector-borne infections; viruses.
MeSH terms
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Adolescent
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Adult
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Afghanistan / epidemiology
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Aged
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Aged, 80 and over
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Antibodies, Viral / immunology
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Child
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Disease Outbreaks / history
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Disease Outbreaks / statistics & numerical data
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Female
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Hemorrhagic Fever Virus, Crimean-Congo* / immunology
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Hemorrhagic Fever, Crimean* / diagnosis
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Hemorrhagic Fever, Crimean* / epidemiology
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Hemorrhagic Fever, Crimean* / history
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Hemorrhagic Fever, Crimean* / virology
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History, 21st Century
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Hospitalization
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Humans
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Immunoglobulin M / immunology
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Male
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Middle Aged
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Symptom Assessment
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Young Adult
Substances
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Antibodies, Viral
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Immunoglobulin M