Crimean-Congo Hemorrhagic Fever, Herat Province, Afghanistan, 2017

Emerg Infect Dis. 2019 Aug;25(8):1596-1598. doi: 10.3201/eid2508.181491. Epub 2019 Aug 17.

Abstract

We studied the clinical and epidemiologic features of an outbreak of Crimean-Congo hemorrhagic fever in Herat Province, Afghanistan. The study comprised 63 patients hospitalized in 2017. The overall case-fatality rate was 22.2%; fatal outcome was significantly associated with a negative IgM test result, longer prothrombin time, and nausea.

Keywords: Afghanistan; CCHF; CCHFV; Crimean-Congo hemorrhagic fever; Crimean-Congo hemorrhagic fever virus; clinical symptomatology; epidemiology; ticks; vector-borne infections; viruses.

MeSH terms

  • Adolescent
  • Adult
  • Afghanistan / epidemiology
  • Aged
  • Aged, 80 and over
  • Antibodies, Viral / immunology
  • Child
  • Disease Outbreaks / history
  • Disease Outbreaks / statistics & numerical data
  • Female
  • Hemorrhagic Fever Virus, Crimean-Congo* / immunology
  • Hemorrhagic Fever, Crimean* / diagnosis
  • Hemorrhagic Fever, Crimean* / epidemiology
  • Hemorrhagic Fever, Crimean* / history
  • Hemorrhagic Fever, Crimean* / virology
  • History, 21st Century
  • Hospitalization
  • Humans
  • Immunoglobulin M / immunology
  • Male
  • Middle Aged
  • Symptom Assessment
  • Young Adult

Substances

  • Antibodies, Viral
  • Immunoglobulin M