Toxoplasmosis Seroprevalence in Romanian Children

Vector Borne Zoonotic Dis. 2019 Nov;19(11):867-869. doi: 10.1089/vbz.2018.2435. Epub 2019 Jun 19.

Abstract

The seroprevalence of Toxoplasma gondii in Romanian children is currently unknown. A serological survey was undertaken to determine T. gondii infection among children from Western Romania. Serum samples of 441 children (aged 1-18 years) were screened for T. gondii immunoglobulin G and immunoglobulin M antibodies. The overall T. gondii seroprevalence was 16.6% and tended to increase with age. Seroprevalence was 18.4% in children from rural regions and 14.7% in those from urban regions. T. gondii antibodies were demonstrated in 19.5% of females and 13.3% of males. This report provided the first seroepidemiological data and evaluated the demographic risk factors regarding T. gondii infection in children from Western Romania. Our results may serve as a basis for a future prevention program for toxoplasmosis.

Keywords: Toxoplasma gondii; Western Romania; children; seroprevalence; toxoplasmosis.

MeSH terms

  • Adolescent
  • Antibodies, Protozoan / blood*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Immunoglobulin G / blood
  • Immunoglobulin M / blood
  • Infant
  • Male
  • Romania / epidemiology
  • Rural Population
  • Seroepidemiologic Studies
  • Toxoplasma / immunology*
  • Toxoplasmosis / epidemiology*
  • Urban Population

Substances

  • Antibodies, Protozoan
  • Immunoglobulin G
  • Immunoglobulin M