The Outbreak of Fentanyl-Related Deaths in Cook County, Illinois, Between October 2015 and December 2017: A Retrospective Study and a Comparison with Previous Data

J Forensic Sci. 2019 Nov;64(6):1735-1742. doi: 10.1111/1556-4029.14114. Epub 2019 Jun 19.

Abstract

The National Institute on Drug Abuse has observed an increase in fentanyl deaths in the United States. One epidemic related to the abuse of fentanyl happened in Cook County in 2005-2007 (350 deaths). Another outbreak of fentanyl deaths occurred in 2015-2017 in the same area. The database of the Cook County Medical Examiner's Office was searched for cases of fentanyl deaths between 2015 and 2017: 1244 deaths were found. A comparison was performed with the previous data: an increase in the number of females was observed in 2015-2017. Also, in 2005-2007, the majority of deaths occurred among African American, while in 2015-2017, Caucasians were more involved. Within our population, some drug combinations were more common in specific demographic subgroups (male/females; Caucasian/African American; and certain age groups). The epidemiology and the most significant drug associations found at the toxicology are discussed, highlighting the usefulness of the knowledge about this outbreak for public health.

Keywords: autopsy; drug overdose; fatal; fentanyl; fentanyl analogs; forensic science; public health; toxicology.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Analgesics, Opioid / analysis
  • Analgesics, Opioid / poisoning*
  • Black or African American / statistics & numerical data
  • Central Nervous System Depressants / analysis
  • Coroners and Medical Examiners
  • Drug Overdose / mortality*
  • Ethanol / analysis
  • Female
  • Fentanyl / analogs & derivatives
  • Fentanyl / analysis
  • Fentanyl / poisoning*
  • Humans
  • Illinois / epidemiology
  • Kidney / chemistry
  • Liver / chemistry
  • Male
  • Middle Aged
  • Muscle, Skeletal / chemistry
  • Opioid-Related Disorders / mortality*
  • Retrospective Studies
  • Sex Distribution
  • White People / statistics & numerical data
  • Young Adult

Substances

  • Analgesics, Opioid
  • Central Nervous System Depressants
  • Ethanol
  • Fentanyl