Hypereosinophilic Syndrome, Cardiomyopathies, and Sudden Cardiac Death in Superinvasive Opisthorchiasis

Vitaly G Bychkov; Vladimir M Zolotukhin; Elena D Khadieva; Svetlana V Kulikova; Ivan M Petrov; Svetlana G Berdinskih; Semen D Lazarev; Lola F Morozova; Evgeny N Morozov

doi:10.1155/2019/4836948

Hypereosinophilic Syndrome, Cardiomyopathies, and Sudden Cardiac Death in Superinvasive Opisthorchiasis

Cardiol Res Pract. 2019 May 9:2019:4836948. doi: 10.1155/2019/4836948. eCollection 2019.

Authors

Vitaly G Bychkov¹, Vladimir M Zolotukhin², Elena D Khadieva³, Svetlana V Kulikova¹, Ivan M Petrov¹, Svetlana G Berdinskih⁴, Semen D Lazarev¹, Lola F Morozova⁵, Evgeny N Morozov^{5

6}

Affiliations

¹ Tyumen State Medical University, Tyumen, Russia.
² Pathology Bureau, Clinical Center "Medical City", Tyumen, Russia.
³ Khanty-Mansiysk State Medical Academy, Khanty-Mansiysk, Russia.
⁴ Tyumen Cardiology Research Center, Tomsk National Research Medical Center, Tyumen, Russia.
⁵ Sechenov University, Moscow, Russia.
⁶ Russian Medical Academy of Continuing Professional Education, Moscow, Russia.

Abstract

Cardiovascular pathology in patients with superinvasive opisthorchiasis is characterized by severe changes in haemodynamics and myocardial metabolism, impaired automatism, excitability, and conduction of the heart muscle. An analysis of 578 cases (medical and outpatient records and reports of pathoanatomical and forensic autopsies) recorded in healthcare facilities treating opisthorchiasis patients with a hyperendemic focus was carried out. We identified a set of cardiac changes in patients with hypereosinophilic syndrome associated with superinvasive opisthorchiasis infection, classified the pathological processes in accordance with ICD-10, and described their pathogenesis.