What Is XNA?

Angew Chem Int Ed Engl. 2019 Aug 19;58(34):11570-11572. doi: 10.1002/anie.201905999. Epub 2019 Jul 19.

Abstract

The term "xeno-nucleic acids", abbreviated XNA, has grown in popularity to the point that it has become a catch-all phrase for almost any unnatural nucleic acid, raising the question: what is XNA and how does it differ from chemically modified DNA?

Keywords: XNA; synthetic biology; xeno-nucleic acid.