Colonization rate of Streptococcus pneumoniae, its associated factors and antimicrobial susceptibility pattern among children attending kindergarten school in Hawassa, southern Ethiopia

BMC Res Notes. 2019 Jun 17;12(1):344. doi: 10.1186/s13104-019-4376-z.

Abstract

Objective: The aim of this study was to determine the colonization rate of Streptococcus pneumoniae, antimicrobial susceptibility pattern and associated risk factors among children attending kindergarten school in Hawassa, Ethiopia.

Results: Out of 317 study participants, 68 (21.5%) were colonized with S. pneumoniae. Colonization rate was significantly associated with factors such as age (3 to 4 years old) (P = 0.01), having a sibling whose age was less than 5 years (P = 0.011), sharing a bed with parents (P = 0.005), cooking within bedroom (P = 0.002), and previous hospitalization (P = 0.004). Forty-four (64.6%), 33 (48.5%), and 2942.6%) of S. pneumoniae isolated were resistant to cotrimoxazole, penicillin, and tetracycline respectively.

Keywords: Hawassa; Nasopharyngeal colonization; S. pneumoniae.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Drug Resistance, Multiple, Bacterial / drug effects*
  • Ethiopia
  • Female
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Nasopharynx / drug effects
  • Nasopharynx / microbiology*
  • Pneumococcal Infections / drug therapy*
  • Pneumococcal Infections / microbiology
  • Risk Factors
  • Schools
  • Streptococcus pneumoniae / drug effects*
  • Streptococcus pneumoniae / isolation & purification
  • Streptococcus pneumoniae / physiology

Substances

  • Anti-Bacterial Agents