Midgut NET With Orbital, Myocardial, Testicular, Lymph Nodal and Pulmonary Metastases Presenting With Bilateral Proptosis-Role of 68Ga-DOTANOC PET/CT

Clin Nucl Med. 2019 Oct;44(10):e595-e596. doi: 10.1097/RLU.0000000000002639.

Abstract

Neuroendocrine tumors (NET) are rare neoplasms and commonly metastasize to liver, lymph nodes and less frequently to bones and lungs. Metastases to other organs are extremely rare and we report a case of NET clinically presenting with bilateral proptosis secondary to metastases in orbits. Ga-DOTANOC PET/CT demonstrated somatostatin receptor overexpressing lesions in bilateral orbits, small intestine, lymph nodes, lungs, heart and testes in the absence of liver metastases.

Publication types

  • Case Reports

MeSH terms

  • Exophthalmos / complications*
  • Heart Neoplasms / complications
  • Heart Neoplasms / secondary
  • Humans
  • Lung Neoplasms / complications
  • Lung Neoplasms / secondary
  • Lymphatic Metastasis
  • Male
  • Middle Aged
  • Neuroendocrine Tumors / diagnostic imaging*
  • Neuroendocrine Tumors / pathology*
  • Orbital Neoplasms / complications
  • Orbital Neoplasms / secondary
  • Organometallic Compounds*
  • Positron Emission Tomography Computed Tomography*
  • Testicular Neoplasms / complications
  • Testicular Neoplasms / secondary

Substances

  • 68Ga-DOTANOC
  • Organometallic Compounds